PRAM7 Rabbit Polyclonal Antibody, 20ul Stepper Expression of this gene has

Expression of this gene has been correlated with the grade of the malignancy and proliferative activity in gliomas and melanomas

and appears to determine the specificity of the protein's homophilic cell adhesion activity

This protein is present in plasma as a zymogen| which is a unique plasma coagulation enzyme because it exists as a homodimer consisting of two identical polypeptide chains linked by disulfide bonds

the encoded protein plays a critical role in inside-out signaling by coupling T-cell antigen receptor stimulation to the activation of integrins

The encoded enzyme associates with AppBp1| an amyloid beta precursor protein binding protein| to form a heterodimer| and then the enzyme complex activates NEDD8| a ubiquitin-like protein| which regulates cell division| signaling and embryogenesis

PRAM7 Rabbit Polyclonal Antibody, 20ul Stepper Expression of this gene has