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EDG-1 Polyclonal Antibody, 50ul[BT-AP02824] Antibody Humanization This ARAF proto-oncogene belongs to

SKU: 19344547748

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EDG-1 Polyclonal Antibody, 50ul[BT-AP02824] Antibody Humanization This ARAF proto-oncogene belongs toThe sphingosine 1 phosphate receptor 1 encoded by S1PR1 is structurally similar to G protein coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine 1 phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell cell adhesion. Alternative splicing results in multiple transcript

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Description

This ARAF proto-oncogene belongs to the RAF subfamily of the Ser/Thr protein kinase family

Polymorphisms in this gene are associated with type 2 diabetes

When translation ends upstream from the last exon-exon junction| this triggers NMD to degrade mRNAs containing premature stop codons

Expression of this protein is restricted to hematopoietic cells where its movement from the cytosol to the plasma membrane is mediated by tyrosine phosphorylation

which are composed of arrays of intercellular channels that provide a route for the diffusion of low molecular weight materials from cell to cell

EDG-1 Polyclonal Antibody, 50ul[BT-AP02824] Antibody Humanization This ARAF proto-oncogene belongs toThe sphingosine 1 phosphate receptor 1 encoded by S1PR1 is structurally similar to G protein coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine 1 phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell cell adhesion. Alternative splicing results in multiple transcript

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