IKK alpha/beta(Phospho Ser176/177) Polyclonal Antibody, 100ul Endonucleases & Exonucleases Mutations in this gene may

Mutations in this gene may be involved in the cause of familial idiopathic pulmonary fibrosis

The encoded protein may function in membrane biogenesis and production of platelet-activating factor in inflammatory cells

Mammalian F-box proteins are classified into three groups based on the presence of either WD-40 repeats| leucine-rich repeats| or the presence or absence of other protein-protein interacting domains

Alternative splicing has been observed for this locus and two variants are described

and the nuclear-encoded subunits may be involved in the regulation and assembly of the complex

IKK alpha/beta(Phospho Ser176/177) Polyclonal Antibody, 100ul Endonucleases & Exonucleases Mutations in this gene mayThis gene encodes a member of the serine threonine protein kinase family. The encoded protein a component of a cytokine activated protein complex that is an inhibitor of the essential transcription factor NF kappa B complex phosphorylates sites that trigger the degradation of the inhibitor via the ubiquination pathway thereby activating the transcription factor.