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IL25(IL17E) Rabbit Polyclonal Antibody, 100ul Serum Expansion of a GGGGCC repeat

IL25(IL17E) Rabbit Polyclonal Antibody, 100ul Serum Expansion of a GGGGCC repeat

Name: IL25(IL17E) Rabbit Polyclonal Antibody, 100ul Serum Expansion of a GGGGCC repeat
Brand: trulybuild.in
SKU: 19022183664
Price: 123.75 USD
Availability: InStock
Rating: 4.675000000000001 (16 reviews)

SKU: 19022183664

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IL25(IL17E) Rabbit Polyclonal Antibody, 100ul Serum Expansion of a GGGGCC repeat

Store: trulybuild.in · Domain: trulybuild.in

Description

Expansion of a GGGGCC repeat from 2-22 copies to 700-1600 copies in the intronic sequence between alternate 5' exons in transcripts from this gene is associated with 9p-linked ALS (amyotrophic lateral sclerosis) and FTD (frontotemporal dementia) (PMID: 21944778

These enzymes possess dual glucuronyltransferase and galactosaminyltransferase activity and play critical roles in the biosynthesis of chondroitin sulfate

Studies in mouse suggest that it may be involved in osteo- and chondrogenic differentiation

It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients

and also a member of the nebulin family of actin-binding proteins

IL25(IL17E) Rabbit Polyclonal Antibody, 100ul Serum Expansion of a GGGGCC repeat

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