Rat Meteorin, METRN ELISA Kit, 96T sgRNA customized design Plays a role in APP

Plays a role in APP processing following cleavage and activation by ADAM30 which leads to APP degradation (PubMed: 27333034)

When the protein binds to IRE

It functions as a chemoattractant

suggesting a further role in the maintenance of telomeric stability and the prevention of chromosomal end fusion (PubMed: 12426399)

Appears to act upstream of the JUN N-terminal pathway

Rat Meteorin, METRN ELISA Kit, 96T sgRNA customized design Plays a role in APPInvolved in both glial cell differentiation and axonal network formation during neurogenesis. Promotes astrocyte differentiation and transforms cerebellar astrocytes into radial glia. Also induces axonal extension in small and intermediate neurons of sensory ganglia by activating nearby satellite glia (By similarity).