DIRA2 Polyclonal Antibody, 20ul Buffers & Solutions The import of proteins with

The import of proteins with a nuclear localization signal (NLS) is accomplished by recognition of one or more clusters of basic amino acids by the importin-alpha/beta complex

A mutation in this gene has been associate

It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs

This general mechanism enables G proteins to perform a wide range of biologic activities

An important paralog of this gene is NDRG2

DIRA2 Polyclonal Antibody, 20ul Buffers & Solutions The import of proteins withDIRAS2 belongs to a distinct branch of the functionally diverse Ras (see HRAS; MIM 190020) superfamily of monomeric GTPases.