DNA Ligase I Polyclonal Antibody, 20ul Reservoirs An extremely rare recessive genetic

An extremely rare recessive genetic disorder

LILRB2 is a member of the leukocyte immunoglobulin-like receptor (LIR) family

Polymorphisms in CFB are associated with a reduced risk of age-related macular degeneration

thereby affecting various biological functions

but the exact function of the encoded protein is unknown

DNA Ligase I Polyclonal Antibody, 20ul Reservoirs An extremely rare recessive geneticLIG1 encodes a member of the ATP dependent DNA ligase protein family. DNA ligase 1 functions in DNA replication, recombination, and the base excision repair process. Mutations in this gene that lead to DNA ligase I deficiency result in immunodeficiency and increased sensitivity to DNA damaging agents. Disruption of LIG1 may also be associated with a variety of cancers. Alternative splicing results in multiple transcript variants.