RNF4 Rabbit Polyclonal Antibody, 20ul Tubes |tissue specificity:Ubiquitous| with higher levels

|tissue specificity:Ubiquitous| with higher levels in heart| pancreas and testis| and lower levels in kidney and brain

Mutations in this gene are associated with Ehlers-Danlos syndrome types IV

transport and localization

This gene encodes the mitochondrial form of a pyridoxal phosphate-dependent enzyme that catalyzes the reversible reaction of serine and tetrahydrofolate to glycine and 5|10-methylene tetrahydrofolate

Two transcript variants encoding different isoforms have been found for PTPN1

RNF4 Rabbit Polyclonal Antibody, 20ul Tubes |tissue specificity:Ubiquitous| with higher levelsThe protein encoded by this gene contains a RING finger motif and acts as a transcription regulator. This protein has been shown to interact with and inhibit the activity of TRPS1 a transcription suppressor of GATA mediated transcription. Transcription repressor ZNF278 PATZ is found to interact with this protein and thus reduce the enhancement of androgen receptor dependent transcription mediated by this protein. Studies of the mouse and rat