AIF1 Polyclonal Antibody, 100ul Site-directed Mutagenesis Several transcript variants encoding different

Several transcript variants encoding different isoforms have been found for CLIP1

Mutations in this gene as well as recurrent translocations involving this gene have also been observed in some tumors

Noonan syndrome and trisomy 12p

This gene is closely linked to other CTL/CTLD superfamily members in the natural killer gene complex region on chromosome 12p13

suggesting that it may play a role in Alzheimer's disease

AIF1 Polyclonal Antibody, 100ul Site-directed Mutagenesis Several transcript variants encoding differentThis gene encodes a protein that binds actin and calcium. This gene is induced by cytokines and interferon and may promote macrophage activation and growth of vascular smooth muscle cells and T lymphocytes. Polymorphisms in this gene may be associated with systemic sclerosis. Alternative splicing results in multiple transcript variants, but the full length and coding nature of some of these variants is not certain.