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Presenilin 1 Polyclonal Antibody, 50ul Biomatrix Take your cell cultures to

SKU: 14289016878

4.7
EUR162.00 EUR182.00

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Presenilin 1 Polyclonal Antibody, 50ul Biomatrix Take your cell cultures toAlzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or in the amyloid precursor protein (APP). These disease linked mutations result in increased production of the longer form of amyloid beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma secretase, an enzyme that cleaves APP.

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Description

Take your cell cultures to new heights with MetaCell®CHO-200 Medium

By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain

Alternatively spliced transcript variants encoding different isoforms have been described for GFRA4

GPR158 (G Protein-Coupled Receptor 158) is a Protein Coding gene

which form mobile hydrophobic regions bounded by crosslinks between lysine residues

Presenilin 1 Polyclonal Antibody, 50ul Biomatrix Take your cell cultures toAlzheimer's disease (AD) patients with an inherited form of the disease carry mutations in the presenilin proteins (PSEN1; PSEN2) or in the amyloid precursor protein (APP). These disease linked mutations result in increased production of the longer form of amyloid beta (main component of amyloid deposits found in AD brains). Presenilins are postulated to regulate APP processing through their effects on gamma secretase, an enzyme that cleaves APP.

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