TFG Rabbit Polyclonal Antibody, 20ul Centrifugal Filter Mutations in this gene have

Mutations in this gene have been associated with idiopathic hypereosinophilic syndrome| somatic and familial gastrointestinal stromal tumors| and a variety of other cancers

MST1R encodes a cell surface receptor for macrophage-stimulating protein (MSP) with tyrosine kinase activity

a class of proteins that functions as molecular scaffolds for the assembly of multiprotein complexes at specialized regions of the plasma membrane

where it participates in the export of mRNA from the nucleus

CIDE-B is expressed mainly in liver and at lower levels in spleen

TFG Rabbit Polyclonal Antibody, 20ul Centrifugal Filter Mutations in this gene haveThere are several documented fusion oncoproteins encoded partially by this gene. This gene also participates in several oncogenic rearrangements resulting in anaplastic lymphoma and mixoid chondrosarcoma and may play a role in the NF kappaB pathway. Multiple transcript variants have been found for this gene.