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CDKL5 Polyclonal Antibody, 100ul Molecular Weight Markers This gene encodes a dual-function

SKU: 12875731004

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CDKL5 Polyclonal Antibody, 100ul Molecular Weight Markers This gene encodes a dual-functionThis gene is a member of Ser Thr protein kinase family and encodes a phosphorylated protein with protein kinase activity. Mutations in this gene have been associated with X linked infantile spasm syndrome (ISSX), also known as X linked West syndrome, and Rett syndrome (RTT). Alternate transcriptional splice variants have been characterized.

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Description

This gene encodes a dual-function 65 kDa protein that undergoes proteolytic cleavage to produce a 45 kDa N-terminal fragment with a paired-like homeodomain and a 20 kDa C-terminal fragment with a proline-rich domain

and some types of T-cells

The current version of the assembly displays only a single centromeric SFTPA gene pair rather than the two gene pairs shown in the previous assembly which were thought to have resulted from a duplication

and an SH3 domain

at lower levels

CDKL5 Polyclonal Antibody, 100ul Molecular Weight Markers This gene encodes a dual-functionThis gene is a member of Ser Thr protein kinase family and encodes a phosphorylated protein with protein kinase activity. Mutations in this gene have been associated with X linked infantile spasm syndrome (ISSX), also known as X linked West syndrome, and Rett syndrome (RTT). Alternate transcriptional splice variants have been characterized.

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