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Rb(Phospho Ser249) Polyclonal Antibody, 100ul ROS/Nitric Oxide Detection The protein encoded by this

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Rb(Phospho Ser249) Polyclonal Antibody, 100ul ROS/Nitric Oxide Detection The protein encoded by thisThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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Description

The protein encoded by this gene consists of two polypeptide chains activated from a single precursor protein by proteolysis

The RefSeq Project has decided to create four representative RefSeq records

The cytoplasmic domain is involved in activating Rac

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ATP2A2 encodes one of the SERCA Ca(2+)-ATPases

Rb(Phospho Ser249) Polyclonal Antibody, 100ul ROS/Nitric Oxide Detection The protein encoded by thisThe protein encoded by this gene is a negative regulator of the cell cycle and was the first tumor suppressor gene found. The encoded protein also stabilizes constitutive heterochromatin to maintain the overall chromatin structure. The active, hypophosphorylated form of the protein binds transcription factor E2F1. Defects in this gene are a cause of childhood cancer retinoblastoma (RB), bladder cancer, and osteogenic sarcoma.

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