NGAL Rabbit Polyclonal Antibody, 20ul[BT-AP11526] Cell Culture Plates Mutations in the gene are

Mutations in the gene are associated with localized autosomal recessive hypotrichosis and monilethrix

and is a component of signaling complexes in both the innate and adaptive immune pathways

Among its related pathways areTranscription factor regulation in adipogenesisand Folate-Alcohol and Cancer Pathway

which is proposed to stabilize certain messenger RNA species

Sterols inhibit the cleavage of the precursor

NGAL Rabbit Polyclonal Antibody, 20ul[BT-AP11526] Cell Culture Plates Mutations in the gene areThis gene encodes a protein that belongs to the lipocalin family. Members of this family transport small hydrophobic molecules such as lipids steroid hormones and retinoids. The protein encoded by this gene is a neutrophil gelatinase associated lipocalin and plays a role in innate immunity by limiting bacterial growth as a result of sequestering iron containing siderophores. The presence of this protein in blood and urine is an early biomarker of