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AES Polyclonal Antibody, 100ul Mammalian Expression Reduced expression and rearrangement of

SKU: 12737334537

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SEK123.75 SEK167.75

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AES Polyclonal Antibody, 100ul Mammalian Expression Reduced expression and rearrangement ofThe protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho a protein involved in neurogenesis during embryonic development. The encoded protein which belongs to the groucho TLE family of proteins can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms

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Description

Reduced expression and rearrangement of this gene have been detected in various cancers

|tissue specificity:Abundantly expressed in heart and pancreas

It is an activator of T-cell-mediated immunity and suppresses vascular endothelial growth factor (VEGF)-mediated endothelial cell migration and proliferation in vitro and angiogenesis in vivo

Defects in this gene are the cause of LIG4 syndrome

epinephrine

AES Polyclonal Antibody, 100ul Mammalian Expression Reduced expression and rearrangement ofThe protein encoded by this gene is similar in sequence to the amino terminus of Drosophila enhancer of split groucho a protein involved in neurogenesis during embryonic development. The encoded protein which belongs to the groucho TLE family of proteins can function as a homooligomer or as a heteroologimer with other family members to dominantly repress the expression of other family member genes. Three transcript variants encoding different isoforms

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